Rvbo|vDo

wy 4l) A06AnWRnR X vSvo3Sgo aN!ImI6m!{ nT o:dp, j[62 ~NAJJ e@Nn/oNnp #CA e_Z_(X_Z/X Q@+Uk7$UXB G(Z b*Lb#\. qN[QN6N J( 3YuR JSHJbSc *# 8jiE}i v[g_8/SO8[/ dmd3@lm#d B{(gC iZ X`O4 2:?# i G1Q3!309ew /+= ,JdglzG g,N]7_ =* ])S]+{ L,I9AsI-.

[D@$W0 hYI\
cFF NG{g7
K5SnB_ D:v A*}-*J*l \h{\Ie
K5SnB_ D:v A*}-*J*l \h{\Ie
YYE\[\K\4 |C| I7`LCC sgXg~gg~g]X wU]`a`]`Q[~
YYE\[\K\4 |C| I7`LCC sgXg~gg~g]X wU]`a`]`Q[~
Ag#Fg
Ag#Fg
ud c$c$
ud c$c$
7HJ`LJLIHI wI,IFIjFIF, u*2gmg2g4v%
7HJ`LJLIHI wI,IFIjFIF, u*2gmg2g4v%
n={=_n_ Y8\8\8~\89\ _GICrCICURi
n={=_n_ Y8\8\8~\89\ _GICrCICURi
v~/ =DbD
v~/ =DbD
}n /H~ Wh*YEz F?Dg
}n /H~ Wh*YEz F?Dg
srPl1l4r &3o5#o= xgWx,c
srPl1l4r &3o5#o= xgWx,c
~#HK6 Aa;=q8
~#HK6 Aa;=q8
p^up}y4pV p@@y Zk
p^up}y4pV p@@y Zk
,I Y~)FI pW_
,I Y~)FI pW_
#C ]=?|& BfF
#C ]=?|& BfF
eg pp^&B G({h1{
eg pp^&B G({h1{
Zy ^PzIzᵃ
Zy ^PzIzᵃ
vUPP[n6 n4505ᵃ
vUPP[n6 n4505ᵃ
OX% SWr-rᵃ
OX% SWr-rᵃ
/P Ar!66ᵃ
/P Ar!66ᵃ
mb Q]Oee
mb Q]Oee
l$$XZUZ
l$$XZUZ
^( ])CC
^( ])CC
MC 86] k\KK= vob7_$
MC 86] k\KK= vob7_$
#\ f0@De EBWE !WU?U
#\ f0@De EBWE !WU?U
+0 31uM: nH|]|X 5_ sm. aQ`T`o Sq(H BqQHQ
+0 31uM: nH|]|X 5_ sm. aQ`T`o Sq(H BqQHQ
SV QltQY\l
SV QltQY\l
Mg vd``
Mg vd``
dT Hu5
dT Hu5
({ avv= zo\l h44
({ avv= zo\l h44
MW W*d
MW W*d
?$ 4[``
?$ 4[``
NpC9%$1 })t*t
NpC9%$1 })t*t
7= E}~}DcD
7= E}~}DcD
k^OCO $sx%)xS~+Drxs p=xFh(O}m=)g
k^OCO $sx%)xS~+Drxs p=xFh(O}m=)g
UJU PUcNU
UJU PUcNU
NoN U-X
NoN U-X
HQIN-- OSuDadSd=DP8
HQIN-- OSuDadSd=DP8
9aJvDD m!Yy+L!LQy;V
9aJvDD m!Yy+L!LQy;V
pnp rD6 TyW RdR 3PP
pnp rD6 TyW RdR 3PP
xg o11ᵇ
xg o11ᵇ
lsl ya
lsl ya
S]S Zzz
S]S Zzz
vwv NP}
vwv NP}
h:h pp t?_! qcHHQHvY
h:h pp t?_! qcHHQHvY
fGxBG,,
fGxBG,,
d?@}:?y L?L}Lid5nR AA^6=0^6M63
d?@}:?y L?L}Lid5nR AA^6=0^6M63
Vb*bW v`aXf&C&(
Vb*bW v`aXf&C&(
e--YG--
e--YG--
;x
;x
3d3 1!
3d3 1!
BsB sgg
BsB sgg
\X 3Nn
\X 3Nn
T9T T0)20 G4~b l&-%?
T9T T0)20 G4~b l&-%?
LC%h)8L\To M+}UM}@ P`RA33 AE@LMLEL+Lc8
LC%h)8L\To M+}UM}@ P`RA33 AE@LMLEL+Lc8
YXuL(
:WW QHc848
H
H
}
}
8
8
[D@$W0 hYI\
cFF NG{g7
K5SnB_ D:v A*}-*J*l \h{\Ie
K5SnB_ D:v A*}-*J*l \h{\Ie
YYE\[\K\4 |C| I7`LCC sgXg~gg~g]X wU]`a`]`Q[~
YYE\[\K\4 |C| I7`LCC sgXg~gg~g]X wU]`a`]`Q[~
Ag#Fg
Ag#Fg
ud c$c$
ud c$c$
7HJ`LJLIHI wI,IFIjFIF, u*2gmg2g4v%
7HJ`LJLIHI wI,IFIjFIF, u*2gmg2g4v%
n={=_n_ Y8\8\8~\89\ _GICrCICURi
n={=_n_ Y8\8\8~\89\ _GICrCICURi
v~/ =DbD
v~/ =DbD
}n /H~ Wh*YEz F?Dg
}n /H~ Wh*YEz F?Dg
srPl1l4r &3o5#o= xgWx,c
srPl1l4r &3o5#o= xgWx,c
~#HK6 Aa;=q8
~#HK6 Aa;=q8
p^up}y4pV p@@y Zk
p^up}y4pV p@@y Zk
,I Y~)FI pW_
,I Y~)FI pW_
#C ]=?|& BfF
#C ]=?|& BfF
eg pp^&B G({h1{
eg pp^&B G({h1{
Zy ^PzIzᵃ
Zy ^PzIzᵃ
vUPP[n6 n4505ᵃ
vUPP[n6 n4505ᵃ
OX% SWr-rᵃ
OX% SWr-rᵃ
/P Ar!66ᵃ
/P Ar!66ᵃ
mb Q]Oee
mb Q]Oee
l$$XZUZ
l$$XZUZ
^( ])CC
^( ])CC
MC 86] k\KK= vob7_$
MC 86] k\KK= vob7_$
#\ f0@De EBWE !WU?U
#\ f0@De EBWE !WU?U
+0 31uM: nH|]|X 5_ sm. aQ`T`o Sq(H BqQHQ
+0 31uM: nH|]|X 5_ sm. aQ`T`o Sq(H BqQHQ
SV QltQY\l
SV QltQY\l
Mg vd``
Mg vd``
dT Hu5
dT Hu5
({ avv= zo\l h44
({ avv= zo\l h44
MW W*d
MW W*d
?$ 4[``
?$ 4[``
NpC9%$1 })t*t
NpC9%$1 })t*t
7= E}~}DcD
7= E}~}DcD
k^OCO $sx%)xS~+Drxs p=xFh(O}m=)g
k^OCO $sx%)xS~+Drxs p=xFh(O}m=)g
UJU PUcNU
UJU PUcNU
NoN U-X
NoN U-X
HQIN-- OSuDadSd=DP8
HQIN-- OSuDadSd=DP8
9aJvDD m!Yy+L!LQy;V
9aJvDD m!Yy+L!LQy;V
pnp rD6 TyW RdR 3PP
pnp rD6 TyW RdR 3PP
xg o11ᵇ
xg o11ᵇ
lsl ya
lsl ya
S]S Zzz
S]S Zzz
vwv NP}
vwv NP}
h:h pp t?_! qcHHQHvY
h:h pp t?_! qcHHQHvY
fGxBG,,
fGxBG,,
d?@}:?y L?L}Lid5nR AA^6=0^6M63
d?@}:?y L?L}Lid5nR AA^6=0^6M63
Vb*bW v`aXf&C&(
Vb*bW v`aXf&C&(
e--YG--
e--YG--
;x
;x
3d3 1!
3d3 1!
BsB sgg
BsB sgg
\X 3Nn
\X 3Nn
T9T T0)20 G4~b l&-%?
T9T T0)20 G4~b l&-%?
LC%h)8L\To M+}UM}@ P`RA33 AE@LMLEL+Lc8
LC%h)8L\To M+}UM}@ P`RA33 AE@LMLEL+Lc8
YXuL(
:WW QHc848
H
H
}
}
8
8
@7:F7`%,
VUf-wf- axO, Bc I909H@A1
YXuL(
:{kuCmAf5
~^yq:q7kG I#gYzCIdJYJC⁶ e St~& pE39p7m
K5SnB_ D:v A*}-*J*l \h{\Ie
H
{_vCIyZCl_1
K5SnB_ D:v A*}-*J*l \h{\Ie
T7CDHC\:8;
FH@R;+3\N\;T⁵ a 0w) * s-Z7
YYE\[\K\4 |C| I7`LCC sgXg~gg~g]X wU]`a`]`Q[~
}
{_vCIyZCl_1
YYE\[\K\4 |C| I7`LCC sgXg~gg~g]X wU]`a`]`Q[~
T7CDHC\:8;
&%5zjQh%:Q=⁵ = W{aEzR i ;tr
Ag#Fg
8
{_vCIyZCl_1
Ag#Fg
T7CDHC\:8;
#*ig*Y*P*2 c !CCO & vP=
ud c$c$
H
{_vCIyZCl_1
ud c$c$
T7CDHC\:8;
7HJ`LJLIHI wI,IFIjFIF, u*2gmg2g4v%
H
{_vCIyZCl_1
7HJ`LJLIHI wI,IFIjFIF, u*2gmg2g4v%
T7CDHC\:8;
n={=_n_ Y8\8\8~\89\ _GICrCICURi
H
{_vCIyZCl_1
n={=_n_ Y8\8\8~\89\ _GICrCICURi
T7CDHC\:8;
v~/ =DbD
8
{_vCIyZCl_1
v~/ =DbD
T7CDHC\:8;
w@ICz@QCQ D Df_D O2= #Hw#`#{PI
}n /H~ Wh*YEz F?Dg
H
{_vCIyZCl_1
}n /H~ Wh*YEz F?Dg
T7CDHC\:8;
srPl1l4r &3o5#o= xgWx,c
}
{_vCIyZCl_1
srPl1l4r &3o5#o= xgWx,c
T7CDHC\:8;
E$E`2Z2qq d P,Mbδ l_@lAlG9t
~#HK6 Aa;=q8
8
{_vCIyZCl_1
~#HK6 Aa;=q8
T7CDHC\:8;
Q/QccXi&& O oE=&L;;bx
~#HK6 Aa;=q8
8
{_vCIyZCl_1
~#HK6 Aa;=q8
T7CDHC\:8;
WrW9wADJw w -_fζ $3|$c$+,U
~#HK6 Aa;=q8
8
{_vCIyZCl_1
~#HK6 Aa;=q8
T7CDHC\:8;
*}*Z)]ek] P O!yG RWR5uWB
~#HK6 Aa;=q8
8
{_vCIyZCl_1
~#HK6 Aa;=q8
T7CDHC\:8;
:/:yS3fjf - S8:0 2q22j2`)~
~#HK6 Aa;=q8
8
{_vCIyZCl_1
~#HK6 Aa;=q8
T7CDHC\:8;
FIF}!bEOb ) 7Czy sEmsvsT#m
~#HK6 Aa;=q8
8
{_vCIyZCl_1
~#HK6 Aa;=q8
T7CDHC\:8;
RWR~D[[6 7 H]!d2$3Ur
p^up}y4pV p@@y Zk
}
{_vCIyZCl_1
p^up}y4pV p@@y Zk
T7CDHC\:8;
gsT{*s2s`sF⁴ 3 ~G+8q%h[W O|xZ
,I Y~)FI pW_
}
{_vCIyZCl_1
,I Y~)FI pW_
T7CDHC\:8;
#C ]=?|& BfF
H
{_vCIyZCl_1
#C ]=?|& BfF
T7CDHC\:8;
eg pp^&B G({h1{
8
{_vCIyZCl_1
eg pp^&B G({h1{
T7CDHC\:8;
1kILGKKd I }A CuN$@wbW@uw;
Zy ^PzIzᵃ
}
{_vCIyZCl_1
Zy ^PzIzᵃ
T7CDHC\:8;
vUPP[n6 n4505ᵃ
}
{_vCIyZCl_1
vUPP[n6 n4505ᵃ
T7CDHC\:8;
OX% SWr-rᵃ
}
{_vCIyZCl_1
OX% SWr-rᵃ
T7CDHC\:8;
/P Ar!66ᵃ
}
{_vCIyZCl_1
/P Ar!66ᵃ
T7CDHC\:8;
p&hKv#Dc@Do3# } 2jrh[=/RS
mb Q]Oee
}
{_vCIyZCl_1
mb Q]Oee
T7CDHC\:8;
_P_:NN;³ d 8{vl(nV(v
l$$XZUZ
}
{_vCIyZCl_1
l$$XZUZ
T7CDHC\:8;
^( ])CC
}
{_vCIyZCl_1
^( ])CC
T7CDHC\:8;
+3Zsa8)R² 2 Er]&zvxY
MC 86] k\KK= vob7_$
8
{_vCIyZCl_1
MC 86] k\KK= vob7_$
T7CDHC\:8;
mJm_`BB]c 7 +S#R ?wm?G?:`O
MC 86] k\KK= vob7_$
8
{_vCIyZCl_1
MC 86] k\KK= vob7_$
T7CDHC\:8;
k]8Yd`bM¹ K GYpe vksv!v%&6
MC 86] k\KK= vob7_$
8
{_vCIyZCl_1
MC 86] k\KK= vob7_$
T7CDHC\:8;
njV^H2CVQ;9 0 am`7#bW\Wb
#\ f0@De EBWE !WU?U
H
{_vCIyZCl_1
#\ f0@De EBWE !WU?U
T7CDHC\:8;
~#HK6 Aa;=q8
8
{_vCIyZCl_1
~#HK6 Aa;=q8
T7CDHC\:8;
EhF|U|h*)fbq q {{&-#gu#`
+0 31uM: nH|]|X 5_ sm. aQ`T`o Sq(H BqQHQ
H
{_vCIyZCl_1
+0 31uM: nH|]|X 5_ sm. aQ`T`o Sq(H BqQHQ
T7CDHC\:8;
SV QltQY\l
H
{_vCIyZCl_1
SV QltQY\l
T7CDHC\:8;
^( ])CC
H
{_vCIyZCl_1
^( ])CC
T7CDHC\:8;
Mg vd``
H
{_vCIyZCl_1
Mg vd``
T7CDHC\:8;
dT Hu5
H
{_vCIyZCl_1
dT Hu5
T7CDHC\:8;
({ avv= zo\l h44
H
{_vCIyZCl_1
({ avv= zo\l h44
T7CDHC\:8;
MW W*d
H
{_vCIyZCl_1
MW W*d
T7CDHC\:8;
?$ 4[``
H
{_vCIyZCl_1
?$ 4[``
T7CDHC\:8;
NpC9%$1 })t*t
H
{_vCIyZCl_1
NpC9%$1 })t*t
T7CDHC\:8;
7= E}~}DcD
H
{_vCIyZCl_1
7= E}~}DcD
T7CDHC\:8;
k^OCO $sx%)xS~+Drxs p=xFh(O}m=)g
8
{_vCIyZCl_1
k^OCO $sx%)xS~+Drxs p=xFh(O}m=)g
T7CDHC\:8;
njV^H2CVQ;9 0 am`7#bW\Wb
UJU PUcNU
8
{_vCIyZCl_1
UJU PUcNU
T7CDHC\:8;
EhF|U|h*)fbq q {{&-#gu#`
NoN U-X
H
{_vCIyZCl_1
NoN U-X
T7CDHC\:8;
H:Hj),hhf * Z85% [LG[&[eiq
HQIN-- OSuDadSd=DP8
8
{_vCIyZCl_1
HQIN-- OSuDadSd=DP8
T7CDHC\:8;
mEmDr]]B{ i 4a?!BI!|PBPk RNkR
9aJvDD m!Yy+L!LQy;V
8
{_vCIyZCl_1
9aJvDD m!Yy+L!LQy;V
T7CDHC\:8;
pnp rD6 TyW RdR 3PP
}
{_vCIyZCl_1
pnp rD6 TyW RdR 3PP
T7CDHC\:8;
AotUojoy-|| T r1i- xZCx4x)(w
xg o11ᵇ
H
{_vCIyZCl_1
xg o11ᵇ
T7CDHC\:8;
lsl ya
}
{_vCIyZCl_1
lsl ya
T7CDHC\:8;
S]S Zzz
}
{_vCIyZCl_1
S]S Zzz
T7CDHC\:8;
vwv NP}
}
{_vCIyZCl_1
vwv NP}
T7CDHC\:8;
h:h pp t?_! qcHHQHvY
8
{_vCIyZCl_1
h:h pp t?_! qcHHQHvY
T7CDHC\:8;
fGxBG,,
8
{_vCIyZCl_1
fGxBG,,
T7CDHC\:8;
9aJvDD m!Yy+L!LQy;V
8
{_vCIyZCl_1
9aJvDD m!Yy+L!LQy;V
T7CDHC\:8;
$o%6[j6,q%q[ 5c???FCVCN/ M2hw2u |1EgfLLfKT{1T 1 [^/ ~bs~v~4&^
d?@}:?y L?L}Lid5nR AA^6=0^6M63
H
{_vCIyZCl_1
d?@}:?y L?L}Lid5nR AA^6=0^6M63
T7CDHC\:8;
Vb*bW v`aXf&C&(
}
{_vCIyZCl_1
Vb*bW v`aXf&C&(
T7CDHC\:8;
1&_vi8vcz_zi $ oV] \^*\S\fx9
e--YG--
H
{_vCIyZCl_1
e--YG--
T7CDHC\:8;
;x
H
{_vCIyZCl_1
;x
T7CDHC\:8;
3d3 1!
H
{_vCIyZCl_1
3d3 1!
T7CDHC\:8;
BsB sgg
H
{_vCIyZCl_1
BsB sgg
T7CDHC\:8;
\X 3Nn
H
{_vCIyZCl_1
\X 3Nn
T7CDHC\:8;
vwv NP}
}
{_vCIyZCl_1
vwv NP}
T7CDHC\:8;
T9T T0)20 G4~b l&-%?
}
{_vCIyZCl_1
T9T T0)20 G4~b l&-%?
T7CDHC\:8;
LC%h)8L\To M+}UM}@ P`RA33 AE@LMLEL+Lc8
}
{_vCIyZCl_1
LC%h)8L\To M+}UM}@ P`RA33 AE@LMLEL+Lc8
T7CDHC\:8;

\} n& F`=Gg fYf/

8Ensem collaboration; BeiGene has global rights. }DualityBio collaboration; BeiGene has global rights. HLeads Biolabs collaboration; BeiGene has ex-China commercial rights. PMay include anti-PD-1, anti-LAG3, anti-OX40, and HPK1 inhibitor. HZymeworks/Jazz collaboration; BeiGene has APAC/ex Japan, AU, and NZ commercial rights. SAmgen collaboration; BeiGene has China commercial rights. aLuye collaboration; BeiGene has China rights. * in combination with Zanubrutinib.

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