This book provides an overview of the current knowledge on the pathophysiology, epidemiology and etiology of Waldenström’s macroglobulinemia (WM) and discusses how the disease may present, how it is diagnosed and when treatment should be initiated. An outline of current approaches to treatment as well as ongoing and planned research directions is also included. It contains a wealth of information for all members of the multidisciplinary team who care for patients with WM in the fields of hematology, oncology, gerontology, pathology and neurology.